Dr. Kathryn Susan Hayward at the Florey Institute of Neuroscience and Mental Health (Australia) for making major impacts on the field of stroke rehabilitation and recovery with focus on individuals with significant loss of arm and hand function in early stadiums of post-stroke (nominated by the Medical Director Catherine Donovan at Bayer Australia).
Category "Medical Sciences"
Dr. Keary M. Engle of Scripps Research Institute La Jolla (USA) for unparalleled contributions at the interface of organometallic chemistry, organic synthesis and catalysis of small molecules (nominated by the Head of Small Molecule Innovation at Bayer Pharmaceuticals Prof. Dr. Michael Brands, and EESA laureate Dr. Bill Morandi of the Max-Planck-Institute in Mühlheim/Ruhr).
Dr. Christoph Engel at University of Regensburg for providing a novel molecular basis for ribosomal RNA synthesis by RNA polymerase in eukaryotic cells (nominated by Otto Bayer laureate Prof. Dr. Patrick Cramer of the Max-Planck-Institute for Biophysical Chemistry in Göttingen).
Dr. Theresa Bunse at DKFZ Heidelberg for outstanding work in the field of tumor immunotherapy – particularly for her contributions towards the development of mutation-specific vaccines for patients with gliomas.
Category “Medical Sciences”
Dr. Christopher Aylett from ETH Zurich (Switzerland) for outstanding research on structural studies to understand the machinery of cellular signalling – his work contributes largely to explain the function of a protein complex implicated in cancer, obesity and neurodegeneration.
Dr. Bill Morandi of MPI for Carbon Resarch in Mülheim an der Ruhr for outstanding contributions in green catalysis – particularly his work on novel methods for a sustainable transformation of hydrocarbons and polyols into high-value building blocks is of high relevance in many areas of medicine and materials science.
Dr. med. Marie-Luise Berres at University Hospital of RWTH Aachen for outstanding contributions to a better understanding of the pathogenetic role of Langerhans Cell in Histiocytosis, a barely understood hematological disorder with incidence similar to acute myelogenous leukemia and a mortality rate of 20 – 40 % in high risk patients (mostly children).
Category “Medical Sciences”
Prof. Cigall Kadoch, MD from Harvard Medical School (USA) for outstanding contributions in understanding and targeting human cancers driven by aberrant chromatin regulators, including the discovery of the mechanism of human synovial sarcoma. One of her most significant findings is that high mutation frequency is present in genes involved in chromatin biology-based processes. Category “Biology”
Prof. Dr. Tanja Gaich of University of Konstanz for the development of a novel method for efficient synthesis of polycyclic natural products from plants and microorganisms – which play an important role in novel drug development strategies. Category “Chemistry”
Dr. Javier Fernandez of Harvard University (USA) for outstanding contributions in materials engineering. Javier Fernández has developed in particular a new biologically inspired material, called “Shrilk”, that replicates the exceptional capabilities of one of nature’s most exceptional materials – insect cuticle. This is a milestone in material design and of high relevance in many applications, including biocompatible packaging and tissue engineering.
Dr. Steven Spoel, University of Edinburgh (UK) for outstanding contributions in gene function research. The work of Steven Spoel has led to a better understanding of how living cells translate environmental signals into changes in gene expression. This knowledge is of high relevance for the understanding of gene expression mechanisms in human, animal and plant cells, and thus likewise important for cancer research, animal health and crop breeding.
Prof. Dr. Abigail Doyle at Princeton University (USA) For the development of novel nickel-catalyzed cross-coupling reactions and the identification of new reagents and strategies for catalytic nucleophilic (radio) fluorination. The work of Abigail Doyle is of high relevance for the application in drug discovery, agro science and material research.
Dr. Volker Presser from INM – Leibniz Institute for New Materials Saarbrücken for outstanding research on novel nanomaterials that can be used in energy storage and transformation technologies. The work of his team focuses on the development of superand pseudocapacitors using state-of-the-art methods like electrospinning and atomic layer deposition. Volker Presser’s research contributes substantially to advancing the technologies urgently needed for efficient large-scale use of renewable energies and for energy storage.
Dr. med. Christiane Opitz at DKFZ Heidelberg for outstanding contributions to the understanding of the relevance of the tryptophan metabolism in cancer biology. Together with her team she discovered the first endogenous ligand for the aryl hydrocarbon receptor (AHR) which is involved in promoting tumor growth and suppressing anti-tumor immune responses. This discovery could enable the development of drugs which are expected to inhibit the malignant phenotype of cancer cells and restore anti-tumor immunity.
Dr. Nuno Maulide of MPI for Carbon Research, Mülheim an der Ruhr, for developing new routes to synthesize highly functional small ring molecules. These molecules are excellent starting points for various active ingredients or natural products. By developing new synthetic methods beyond well-established chemical reactions the Maulide group has discovered unprecedented new phenomena and introduced novel concepts in the field of asymmetric catalysis to be used in all Life Sciences.
Prof. Dr. Arne Thomas at Technical University Berlin For outstanding research contributions in the area of functional materials. The work of Arne Thomas discloses new pathways for the synthesis of highly porous materials. These materials provide new solutions for long unsolved technical challenges, because their properties can be adapted to a wide range of applications, e.g. for gas storage, catalysis support, purification and separation purposes, for column chromatography and ion exchange, and as insulation material.
Dr. Cristobal Uauy of John Innes Center in Norwich (UK) for outstanding research contributions in the area of crop genetics. Among a number of high-class achievements, Cristobal Uauy cloned the first QTL (Quantitative Trait Locus) in wheat, he identified a resistance gene against wheat yellow rust pathogen, and he is very active in the translation of basic research results into applied crop breeding. His scientific work provides the basis for a powerful new toolkit for improved crop productivity, and thus opens the horizon for new strategies in wheat breeding. Category "Biology"
Dr. Andreas Bender from University of Cambridge (UK) for outstanding research work in the field of cheminformatics and the development of new prediction models for drug properties. The work of Andreas Bender discloses new opportunities for a better prediction of modes of action of drugs with in-silico methods, and thus promotes the efficient development of pharma-ceutical products on the road from the idea to an optimized drug candidate.
Dr. Andreas Walther of Aalto University, Helsinki (Finland) for the development of innovative, pearlescent biomimetic materials that exhibit impressive properties in terms of their mechanical stability and flame retardance. This makes them very interesting for use in maritime, aviation and aerospace applications.
Prof. Dr. Oliver Daumke at Max Delbrück Center for Molecular Medicine, Berlin, in recognition of his contributions to the understanding of the structure and function of GTP-binding (G) proteins. G proteins can act as molecular switches that control growth signals in biological cells. Other G proteins function as molecular motors that deform cellular membranes. Prof. Daumke investigates the differences and similarities between these two classes of G proteins.
Prof. Dr. Nicolai Cramer, École polytechnique fédérale de Lausanne (Switzerland) for the developments of new catalytic organometallic reactions for activation of carbon-hydrogen and carbon-carbon bonds. With his research he contributes to the field of production of complex active and natural substances.
Dr. Jürgen Groll, RWTH Aachen in recognition of his outstanding contributions to the development of new types of biocompatible polymeric hydrogels. The new hydrogels enable more targeted drug transport and controlled release in target tissues, thereby facilitating lower dosages of drugs and helping to reduce their side effects.
Dr. Noriyuki Nishimura, University of California, San Diego (USA) in recognition of his outstanding contributions to the identification and characterization of specific stress hormone receptors in plants. These receptors ensure that plants are better able to survive stress conditions such as drought. The work of Dr. Nishimura greatly facilitates the ability to discover new ways to ensure food supplies for a growing world population.
Dr. Tobias Ritter, Harvard University (USA) in recognition of his detailed investigations into fluorination reactions. His new method of integrating fluorine highly selectively in aromatic substances by mild and simple means is a significant advance for active ingredient research in medicinal chemistry and crop protection.